Primary effusion lymphoma
نویسندگان
چکیده
منابع مشابه
Primary effusion lymphoma.
Primary effusion lymphoma (PEL) is a rare HIV-associated non-Hodgkin's lymphoma (NHL) that accounts for approximately 4% of all HIV-associated NHL. PEL has a unique clinical presentation in having a predilection for arising in body cavities such as the pleural space, pericardium, and peritoneum. PEL cells are morphologically variable with a null lymphocyte immunophenotype and evidence of human ...
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The activation, proliferation and survival of lymphocytes depend on the antigen receptor-induced formation of cytoplasmic signaling complexes that control specific transcriptional pathways. The protease MALT1 has an essential role in lymphocyte activation and lymphoma development [1, 2]. Upon antigen receptor triggering, MALT1 is recruited to the so-called CBM complex, formed by the assembly of...
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Primary effusion lymphoma (PEL) is a unique form of non-Hodgkin lymphoma, usually seen in severely immunocompromised, HIV-positive patients. PEL is related to human herpesvirus-8 (HHV-8) infection, and it usually presents as a lymphomatous body cavity effusion in the absence of a solid tumor mass. There have been very few case reports of HIV-positive patients with HHV-8-positive solid tissue ly...
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Primary effusion lymphoma (PEL) is a rare form of aggressive B cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). Current chemotherapy approaches result in dismal outcomes, and there is an urgent need for new PEL therapies. Previously, we established, in a direct xenograft model of PEL-bearing immune-compromised mice, that treatment with the proteasome inhibitor, bortezomib...
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http://bloodjournal.hematologylibrary.org/content/101/6/2321.full.html Updated information and services can be found at: (4217 articles) Neoplasia (3667 articles) Clinical Trials and Observations (746 articles) Apoptosis Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information ...
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ژورنال
عنوان ژورنال: Cancer
سال: 2007
ISSN: 0008-543X
DOI: 10.1002/cncr.22691